We work in a range of overlapping areas, including genomics, other ‘omics, pharmacology, medical bioinformatics, molecular biology, imaging, and gene therapy.
Nitroxides can undergo one- or two-electron reduction reactions to hydroxylamines or oxammonium cations, respectively, which themselves are interconvertible, thereby providing redox metabolic actions.
When trying strings with South Denmark Philharmonic’s violinist Jakob Elmedal Johansen, we talked about the way musicians view instruments, bows and strings.
Tempol is a redox cycling nitroxide that promotes the metabolism of many reactive oxygen species (ROS) and improves nitric oxide bioavailability. It has been studied extensively in animal models of oxidative stress.