When it comes to your health, nothing is more valuable than time. Quickly find the best doctors, latest medical advances, and active clinical trials with MediFind. Our goal is to dramatically reduce the amount of time and frustration you…
When it comes to your health, nothing is more valuable than time. Quickly find the best doctors, latest medical advances, and active clinical trials with MediFind. Our goal is to dramatically reduce the amount of time and frustration you…
Enoyl-acyl carrier protein reductase (FabI) catalyzes a rate-controlling step in bacterial fatty-acid synthesis and is a target for antibacterial drug development. A phylogenetic analysis shows that FabIs fall into four divergent clades.
The mechanism of action of AFN-1252, a selective inhibitor of Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI), which is involved in fatty acid biosynthesis, was confirmed by using biochemistry, macromolecular synthesis…