Natural killer (NK) cells play a critical role in the innate immune response against cytomegalovirus (CMV) infections. Although CMV encodes several gene products committed to evasion of adaptive immunity, viral modulation of NK cell…
Jai RANA, Head of Department | Cited by 4,071 | of National Bureau of Plant Genetic Resources, New Delhi (Nbpgr) | Read 146 publications | Contact Jai RANA
Mohamad Karimi, Associate Professor | Cited by 2,700 | of Shiraz University of Medical Sciences, Shiraz (SUMS) | Read 185 publications | Contact Mohamad Karimi
Vaccinia virus (VV) is an extensively studied, prototypic member of the Poxviridae family. It is a large virus with a double-stranded DNA genome of ∼200 kbp encoding ∼250 genes [1]. VV has a broad cellular tropism and infects almost any cell…
How receptor acquisition correlates with the functional maturation of natural killer (NK) cells is poorly understood. We used quantitative real-time polymerase chain reaction (PCR) assays to compare NKG2 and killer immunoglobulin-like…
We have used Carlin to identify intrinsic biases in the activity of fetal liver hematopoietic stem cell (HSC) clones and to uncover a previously unappreciated clonal bottleneck in the response of HSCs to injury.
The classic model for neurodegeneration due to mutations in DNA repair genes holds that DNA damage accumulates in the absence of repair, resulting in the death of neurons. This model was originally put forth to explain the dramatic loss of…
Andrew Lackner, Professor of Microbiology, Immunology and Pathology | Cited by 29,314 | of Tulane University, New Orleans (TU) | Read 378 publications | Contact Andrew Lackner