Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated…
Mammalian female meiosis is error prone, with rates of meiotic chromosome missegregations strongly increasing towards the end of the reproductive lifespan. A strong reduction of BubR1 has been observed in oocytes of women approaching…
Brian "Psychochild" Green (1973 – 6 August 2020) [1 ] [2 ] was an American software engineer, game developer and game designer known for his work on one of the first 3D, Mmorpg's in existence, Meridian 59 (released 1996).
Chromosome missegregation in germ cells is an important cause of unexplained infertility, miscarriages, and congenital birth defects in humans. However, the molecular defects that lead to production of aneuploid gametes are largely unknown…
A number of these PK genes, including Fg03146 and Fg04770 that are unique to filamentous fungi, are dispensable for hyphal growth and likely encode novel fungal virulence factors.
Peer reviews are different from general articles about Wikipedia because they give a critique of one or more articles specifically, often noting problems or highlighting their good qualities.
Waarom de Engelse taal de facto, dus is niet officieel, en waarom het spaans officiële ambtenaar in Puerto RICO en Puerto RICO is onderdeel van de verenigde staten en Puerto RICO is als officiële taal en dit is een onderdeel van de…
Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity, and fidelity of the major events of the cell cycle. These include growth to the appropriate cell size, the replication and integrity of the chromosomes…
Nuclear 3'-end-polyadenylation is essential for the transport, stability and translation of virtually all eukaryotic mRNAs. Poly(A) tail extension can also occur in the cytoplasm, but the transcripts involved are incompletely understood…