We have investigated the intracellular signaling mechanisms underlying the release of nitric oxide (NO) evoked by β-adrenoceptor (AR) agonists in urinary bladder strips and cultured bladder urothelial cells from adult rats.
The term 'inconspicuous penis' refers to a group of anatomical abnormalities in which the penis looks smaller than is expected. Micropenis can be defined as 'true micropenis'-which results from a defect in the
What factors contribute to the development of an inconspicuous penis in children?The paper identifies congenital, developmental, and iatrogenic causes, including buried, webbed, and trapped penis configurations.How prevalent is the inconspicuous penis condition among circumcised children?It has been reported that 9% of patients seeking initial circumcision and 63% of those referred for revision exhibit signs of an inconspicuous penis.What is the distinction between true micropenis and concealed penis?True micropenis is defined as a stretched penile length at least 2.5 SD below the mean, while concealed penis includes conditions like buried and webbed penis, where the length appears normal.
Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of prognosis and a major determinant of renal insufficiency…
The 28 mammalian members of the super-family of transient receptor potential (TRP) channels are cation channels, mostly permeable to both monovalent and divalent cations, and can be subdivided into six main subfamilies: the TRPC (canonical…
Swarming motility by the urinary tract pathogen Proteus mirabilis has been a long-studied but little understood phenomenon. On agar, a P. mirabilis colony grows outward in a bull's-eye pattern formed by consecutive waves of rapid swarming…
Diagnostic IR procedures are those intended to help make a diagnosis or guide further medical treatment, and include image-guided biopsy of a tumor or injection of an imaging contrast agent into a hollow structure, such as a blood vessel or…
Erectile dysfunction is a multidimensional but common male sexual dysfunction that involves an alteration in any of the components of the erectile response, including organic, relational and psychological.
Constipation is a frequently reported bowel symptom in the elderly with considerable impact on quality of life and health expenses. Disease-related morbidity and even mortality have been reported in the affected frail elderly.