PART FIVE : Enter THE MAN FROM Chloride On the day Michael Edwardes became British Leyland Chairman, 1 November 1977, some 1500 workers at Triumph, Speke Number Two, walked out only a few hours after they had resumed work.
Mutations in STAT1 cause a broad spectrum of disease, ranging from severe viral and bacterial infections (amorphic alleles), to mild disseminated mycobacterial disease (hypomorphic alleles), to chronic mucocutaneous candidiasis…
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system.
Cells from Cockayne syndrome patients and a mouse model of the disease show increased metabolism as a result of impaired autophagy-mediated removal of damaged mitochondria.