Clostridioides difficile is responsible for post-antibiotic diarrhea and most of the pseudomembranous colitis cases. Multiple recurrences, one of the major challenges faced in C. difficile infection (CDI) management, can be considered as…
Julio Plaza-Díaz currently works at the Department of Biochemistry and Biotechnology, Universitat Rovira i Virgili. Julio does research in Microbiology, Biotechnology and Molecular Biology.
We show that the premetastatic niche in the liver is induced by bacteria dissemination from primary CRC. We report that tumor-resident bacteria Escherichia coli disrupt the gut vascular barrier (GVB), an anatomical structure controlling…
Clostridium difficile (CD) infection (CDI) increases patient morbidity, mortality and healthcare costs. Antibiotic treatment induces gut dysbiosis and is both a major risk factor for CD colonization and treatment of CDI.
Yeasts and their glycan components can have a beneficial or adverse effect on intestinal inflammation. Previous research has shown that the presence of Saccharomyces cerevisiae var.
Microbes hold promise as an inflammatory bowel disease (IBD) therapy. Lactococcus lactis, which has not been appreciated as a beneficial microbe, attenuated colitis in three preclinical mouse IBD models.
One way to improve both the ecological performance and functionality of probiotic bacteria is by combining them with a prebiotic in the form of a synbiotic. However, the degree to which such synbiotic formulations improve probiotic strain…