The future systematic mapping of variants that confer susceptibility to common diseases requires the construction of a fully informative polymorphism map. Ideally, every base pair of the genome would be sequenced in many individuals.
Eugene Maraskovsky, Executive Director | Cited by 22,909 | of University of Melbourne, Melbourne (MSD) | Read 187 publications | Contact Eugene Maraskovsky
Positive organizational scholarship rigorously seeks to understand what represents the best of the human condition based on scholarly research and theory.
An important question in memory development is understanding the differences between effector CD8 T cells that die versus effector cells that survive and give rise to memory cells.
Karthickeyan SMK, Professor | Cited by 376 | of Tamil Nadu Veterinary and Animal Sciences University, Chennai (Tanuvas) | Read 103 publications | Contact Karthickeyan SMK
T cell dysfunction is a hallmark of many cancers, but the basis for T cell dysfunction and the mechanisms by which antibody blockade of the inhibitory receptor PD-1 (anti-PD-1) reinvigorates T cells are not fully understood.
Heart development is tightly regulated by signaling events acting upon a defined number of progenitor and differentiated cardiac cells. While loss-of-function of these signaling pathways leads to congenital malformation, the consequences of…