Single-Neuron Sequencing Analysis of L1 Retrotransposition and…
We then genotyped single cortical cells to characterize the mosaicism of a somatic AKT3 mutation identified in a child with hemimegalencephaly.
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Hua XIAO | Research scientist | PhD | National Institutes of…
Hua XIAO, Research scientist | Cited by 7,018 | of National Institutes of Health, Bethesda (NIH) | Read 95 publications | Contact Hua XIAO
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Antisense Promoter of Human L1 Retrotransposon Drives…
In the human genome, retrotranspositionally competent long interspersed nuclear elements (L1Hs) are involved in the generation of processed pseudogenes and mobilization of unrelated sequences into existing genes.
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Eye Selector Logic for a Coordinated Cell Cycle Exit…
Selector genes are transcription factors that instruct the development of organs. The processes under the control of selector genes include the assignation of cell fates and their organ-specific responses to extracellular signals [1].
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Breviscapine ameliorates hypertrophy of cardiomyocytes induced…
To investigate the influence of breviscapine on high glucose-induced hypertrophy of cardiomyocytes and the relevant mechanism in vitro and in vivo. Cultured neonatal cardiomyocytes were divided into i) control; ii) high glucose…
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Induction of protein catabolism in myotubes by 15(S…
The potential role of 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE) as an intracellular signal for increased protein catabolism and induction of the expression of key components of the ubiquitin–proteasome proteolytic pathway induced by a…
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Evolutionary Diversification of Plant Shikimate Kinase Gene…
Shikimate kinase (SK; EC 2.7.1.71) catalyzes the fifth reaction of the shikimate pathway, which directs carbon from the central metabolism pool to a broad range of secondary metabolites involved in plant development, growth, and stress…
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CTCF mediates long-range chromatin looping and local histone…
CTCF (Ccctc-binding factor) binds sites around the mouse β-globin locus that spatially cluster in the erythroid cell nucleus. We show that both conditional deletion of CTCF and targeted disruption of a DNA-binding site destabilize these…
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Common Cell Shape Evolution of Two Nasopharyng…
The aforementioned species are part of the normal human NP microbiome where they generally live in asymptomatic symbiosis.
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(PDF) Genomic analysis of heat-shock factor targets in…
We have used a chromatin immunoprecipitation-microarray (ChIP-array) approach to investigate the in vivo targets of heat-shock factor (Hsf) in Drosophila embryos. We show that this method identifies Hsf target sites with high fidelity and…
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