The Confederation of North, Central America and Caribbean Association Football, [1 ] [a ] abbreviated as Concacaf (/ ˈ k ɒ ŋ k ə k æ f/ KONG-kə-kaf; typeset for branding purposes since 2018 as Concacaf), [2 ] is one of FIFA's six…
To date, the effects of specific modification types and sites on protein lifetime have not been systematically illustrated. Here, we describe a proteomic method, DeltaSILAC, to quantitatively assess the impact of site-specific…
Populations living in remote rural communities would benefit from rapid, highly sensitive molecular, DNA-based diagnostics to inform the correct and timely treatment of infectious diseases.
Cytochrome P450 3A4 (CYP3A4) metabolizes ~50% of all clinically used drugs. Although CYP3A4 expression varies widely between individuals, the contribution of genetic factors remains uncertain.
Como con los metales y los no metales, los semimetales (también conocidos como metaloides) comprenden una de las tres categorías de elementos químicos siguiendo una clasificación de acuerdo con las propiedades de enlace e ionización. [1…
Metformin activates both PRKA and SIRT1. Furthermore, autophagy is induced by either the PRKA-MTOR-ULK1 or SIRT1-FOXO signaling pathways. We aimed to elucidate the mechanism by which metformin alleviates hepatosteatosis by examining the…
Major depressive disorder (MDD) has been associated with reduced leukocyte telomere length (LTL). It is not known, however, whether psychosocial and behavioral protective factors moderate this association.