The activity of the SCFskp2 E3 ligase is required for the proteolytic turnover of several proteins involved in cell cycle control and transcriptional regulation. Loss of skp2 in the mouse leads to a complex phenotype including changes in…
Although epidemiological data have indicated that a strong negative association exists between coffee consumption and the prevalence of obesity-associated diseases, the molecular mechanisms by which coffee intake prevents obesity-associated…
1. Olson JS, WattsJA, AllisonLJ (1983) Carbon in live vegetation of major world ecosystems (ORNL-5862). Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee.
Flaxseed is a rich source of the plant lignan secoisolariciresinol diglucoside (SDG) which is metabolized into mammalian lignans enterodiol (ED) and enterolactone (EL) in the digestive tract.
Rincón is the son of the Colombian international footballer Freddy Rincón, who played for European teams such as Real Madrid and Napoli, and also in the Colombia national team. [1 ] He has a younger step brother, Andres Caceres, who plays…
Histone deacetylases (Hdacs) regulate gene expression by deacetylating histones and also modulate the acetylation of a number of nonhistone proteins, thus impinging on various cellular processes.