The cannabinoid receptor 1 (CB1) is the principal target of the psychoactive constituent of marijuana, the partial agonist Δ9-tetrahydrocannabinol (Δ9-THC)1. Here we report two agonist-bound crystal structures of human CB1 in complex with a…
Crispr/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/Crispr associated with protein CAS9) is a genome-editing tool that has been extensively used in the last five years because of its novelty, affordability, and…