Combined inhibition of MEK and Plk1 has synergistic anti-tumor…
About one third of cancers harbor activating mutations in rat sarcoma viral oncogene homolog (RAS) oncogenes. In melanoma, aberrant neuroblastoma-RAS (NRAS) signaling fuels tumor progression in about 20% of patients.
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AMPK governs lineage specification through Tfeb-dependent…
Young et al. show that AMPK plays critical roles in lineage specification. AMPK−/− embryoid bodies exhibited reduced levels of Tfeb, a master transcriptional regulator of lysosomes, leading to diminished endolysosomal function.
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Comoros – CAHF | Centre for Affordable Housing Finance Africa
Despite this, recent media reports highlight notable strides made by the government. Over 50 projects, including village centres, have been completed as part of the Cyclone Kenneth recovery programme.
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Targeting the hedgehog transcription factors GLI1 and GLI2…
BRAF inhibitor (Brafi) therapy for melanoma patients harboring the V600E mutation is initially highly effective, but almost all patients relapse within a few months. Understanding the molecular mechanisms underpinning Brafi-based therapy is…
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Old English Grammar - Wright J. - 1998
The (§ 4I) and (§ 48) were also nasalized vowels in prim. Germanic. § 41. e became i under the following circumstances :-- x. Belote a nasal+consonant, as Goth.
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AFib Ablation & Esophageal Resource Library – EPreward
The articles below were acquired from free internet access over the past 10 years while developing the EsoSure Esophageal Retractor.
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