Persistence of intact HIV-1 proviruses in the brain during…
Genome-intact HIV-1 proviruses were detected in autopsy samples from the brain of ART-treated persons living with HIV, indicating that the virus can persist in the central nervous system.
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Molecular profiling of experimental endometriosis identified…
To validate a rat model of endometriosis using cDNA microarrays by identifying common gene expression patterns beween experimental and natural disease. Autotransplantation rat model.
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The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors…
Nucleos(t)ide analog therapy blocks DNA synthesis by the hepatitis B virus (HBV) reverse transcriptase and can control the infection, but treatment is life-long and has high costs and unpredictable long-term side effects.
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Macrophage tropism of HIV-1 depends upon efficient cellular…
Retroviruses utilize cellular dNTPs to perform proviral DNA synthesis in infected host cells. Unlike oncoretroviruses, which replicate only in dividing cells, lentiviruses, such as HIV-1 and SIV, are capable of efficiently replicating in…
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An antigenic atlas of HIV-1 escape from broadly neutralizing…
Anti-HIV broadly neutralizing antibodies (bnAbs) have revealed vaccine targets on the virus’s envelope (Env) protein and are themselves promising immunotherapeutics. The efficacy of bnAb-based therapies and vaccines depends in part on how…
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Differences in HIV-1 reservoir size, landscape characteristics…
Extremely early antiretroviral therapy during HIV-1 subtype C infection leads to faster decline in genome-intact viruses, reduced genetic complexity, and immune escape, and may enhance reservoir clearance with additional interventional…
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Transient regulatory T cell manipulation is limited by anti…
We studied germinal center responses and HIV-1 antibody development in rhesus macaques (RMs) immunized with sequential CH505 gp120 envelopes (Envs), with or without anti-CD25 monoclonal antibody (mAb).
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Vasudevan Achuthan | Scientist | Doctor of Philosophy | Crispr…
Vasudevan Achuthan, Scientist | Cited by 539 | of Crispr Therapeutics, Cambridge | Read 20 publications | Contact Vasudevan Achuthan
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Ccaaa - 2020 World Day for Audiovisual Heritage
The World Day for Audiovisual Heritage has become a key initiative for both Unesco and the Coordinating Council of Audiovisual Archives Associations (Ccaaa) to honour audiovisual preservation professionals and institutions that help to…
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