Inhibition of Pparγ function by TNF-α contributes to metabolic disorder in glucose and fatty acids under inflammation and cancer, but the molecular mechanism remains to be fully understood.
In contrast, heterozygous mutations, T12M, G533R and A746T, have small or minimal effects on protein stability. We further demonstrate that ATP13A2 is normally localized to cytoplasmic acidic vesicular membranes in mammalian neurons…
Strains of the filamentous fungus Cochliobolus carbonum that produce the host-selective compound HC-toxin, a cyclic tetrapeptide, are highly virulent on certain genotypes of maize (Zea mays L.). Production of HC-toxin is under the control…
The direct link between inflammatory bowel diseases and colorectal cancer is well documented. Previous studies have reported that some lactic acid bacterial strains could inhibit colon cancer progression however; the exact molecules…