When autophagy is induced, ULK1 phosphorylates Ambra1, releasing the autophagy core complex from the cytoskeleton and allowing its relocalization to the ER membrane to nucleate autophagosome formation.
Gene expression can be modulated by chromatin changes induced by histone acetylation and deacetylation. Acetylation of histone lysine residues by acetyltransferases is associated with transcriptionally active chromatin, whereas the removal…
We investigated maternal obesity in inbred SM/J mice by assigning females to a high-fat diet or a low-fat diet at weaning, mating them to low-fat-fed males, cross-fostering the offspring to low-fat-fed SM/J nurses at birth, and weaning the…
Increased neurogenesis has been reported in neurodegenerative disease, but its significance is unclear. In a mouse model of prion disease, Gomez-Nicola et al. detect increased neurogenesis in the dentate gyrus that partially counteracts…
Arheje so pod imenom Archebacteria prvotno prištevali k bakterijam, vendar so raziskave v zadnjih desetletjih pokazale, da so arheje posebna skupina organizmov, ki se razlikujejo tako od bakterij kot od evkariontov.
Labeling of GMO products in the marketplace is required in 64 countries. [3 ] Labeling can be mandatory up to a threshold GM content level (which varies between countries) or voluntary.
Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1 ] Gene transcription occurs in both eukaryotic and prokaryotic…