Tudor domain protein Tdrd6 is required for spermiogenesis…
Chromatoid bodies (CBs) are characteristic spermatid organelles, which were suggested to function in RNA storage and small RNA processing, but whose functions remain largely unknown.
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Oocyte Generation in Adult Mammalian Ovaries by Putative Germ…
It has been suggested that germline stem cells maintain oogenesis in postnatal mouse ovaries. Here we show that adult mouse ovaries rapidly generate hundreds of oocytes, despite a small premeiotic germ cell pool.
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Computer-Assisted Annotation of Murine Sertoli Cell Small RNA…
Mammalian genomes encode a large number of small noncoding RNAs (sncRNAs) that play regulatory roles during development and adulthood by affecting gene expression. Several sncRNA species, including microRNAs (miRNAs), piwi-interacting RNAs…
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Cytokine/Jak/Stat signaling mediates regeneration and…
Cells in intestinal epithelia turn over rapidly due to damage from digestion and toxins produced by the enteric microbiota. Gut homeostasis is maintained by intestinal stem cells (ISCs) that divide to replenish the intestinal epithelium…
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The Genome Sequence of Methanosphaera stadtmanae Reveals Why…
Methanosphaera stadtmanae has the most restricted energy metabolism of all methanogenic archaea. This human intestinal inhabitant can generate methane only by reduction of methanol with H2 and is dependent on acetate as a carbon source.
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