Covalently closed circular DNA (cccDNA), the nuclear form of hepatitis B virus (HBV), is synthesized by repair of the relaxed circular (RC) DNA genome. Initially, cccDNA is derived from RC DNA from the infecting virion, but additional…
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Projections are visible in cryo-EM pictures (Figure 1C). The outer, detergent-sensitive, envelope contains the surface proteins and surrounds an icosahedral nucleocapsid core that is composed of one major protein species, the core protein.
Summarizing the UATs available for bacterial respiratory infections, current guidelines on their usage, & their impact on clinical outcomes and targeted therapy
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