The Basque Swimming Federation (Basque: Euskal Igeriketa Erakundea, EIF; Spanish: Federación Vasca de Natación, FVN) is the body responsible for managing swimming sport in the Basque Country autonomous region. [1 ] [2 ] Its offices are in…
ISO 3166-1 [1 ] es la primera parte del estándar internacional de normalización ISO 3166, publicado por la Organización Internacional de Normalización (ISO), que proporciona códigos para los nombres de países y otras dependencias…
A thunderstorm, also known as an electrical storm or a lightning storm, is a storm characterized by the presence of lightning and thunder. [1 ] Relatively weak thunderstorms are sometimes called thundershowers. [2 ] Thunderstorms occur in…
Loss of the CDKN2A tumor suppressor is associated with melanoma metastasis, but the mechanisms connecting the phenomena are unknown. Using Crispr-Cas9 to engineer a cellular model of melanoma initiation from primary human melanocytes, we…
Formation of highly organized neocortical structure depends on the production and correct placement of the appropriate number and types of neurons. POU homeodomain proteins Brn-1 and Brn-2 are coexpressed in the developing neocortex, both…
The complexity of the human brain has made it difficult to study many brain disorders in model organisms, and highlights the need for an in vitro model of human brain development. We have developed a human pluripotent stem cell-derived 3D…
The basic helix-loop-helix (bHLH) transcription factor Math5 (Atoh7) is transiently expressed during early retinal histogenesis and is necessary for retinal ganglion cell (RGC) development.
Nuclear 3'-end-polyadenylation is essential for the transport, stability and translation of virtually all eukaryotic mRNAs. Poly(A) tail extension can also occur in the cytoplasm, but the transcripts involved are incompletely understood…