ISO 3166-1 [1 ] es la primera parte del estándar internacional de normalización ISO 3166, publicado por la Organización Internacional de Normalización (ISO), que proporciona códigos para los nombres de países y otras dependencias…
In chronic myelogenous leukemia, reciprocal translocation between chromosome 9 and chromosome 22 generates a chimeric protein, Bcr-Abl, that leads to hyperactivity of tyrosine kinase-linked signaling transduction.
BirA ligase, a prokaryotic ortholog of holocarboxylase synthetase (HCS), is known to biotinylate proteins. Here, we tested the hypothesis that BirA ligase catalyzes biotinylation of eukaryotic histones.
The sodium-dependent multivitamin transporter (SMVT) is essential for mediating and regulating biotin entry into mammalian cells. In cells, biotin is covalently linked to histones in a reaction catalyzed by holocarboxylase synthetase (HCS…
Studies in the past have illuminated the potential benefit of resveratrol as an anticancer (pro-apoptosis) and life-extending (pro-survival) compound. However, these two different effects were observed at different concentration ranges.