64d0abd9-9c81-4e3d-8ccf-55f085845657 | Tgacv

Střední škola technická, gastronomická a automobilní, Chomutov, příspěvková organizace
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Molecular basis and genetic testing strategies for diagnosing…

The TNXB gene encodes an extracellular matrix glycoprotein, tenascin-X (TNX), and defects in TNXB cause Ehlers-Danlos syndrome.
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Genetics of eating disorders in the genome-wide era - PMC

Enabled by advances in high throughput genomic sequencing and an unprecedented level of global data sharing, molecular genetic research is beginning to unlock the biological basis of eating disorders.
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Vitamin C–squalene bioconjugate promotes epidermal thickening…

Vitamin C (Vit C) benefits to human skin physiology notably by stimulating the biosynthesis of collagen. The main cutaneous collagens are types I and III, which are less synthesized with aging.
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Differential Genetic Associations for Systemic Lup…

Table S1 presents the genomic control inflation factor (λGC) for each analysis prior to and after adjustment for population stratification.
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DNA Methylation Profiling of the Human Major Histocompatibility…

The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine–guanine dinucleotides, DNA methylation is intimately involved in diverse…
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FOXO1 is Required for Binding of PR on IRF4, Novel…

The forkhead box O1A (FOXO1) is an early-induced target of the protein kinase A pathway during the decidualization of human endometrial stromal cells (Hescs). In this study we identified the cistrome and transcriptome of FOXO1 and its role…
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Adebowale A. Adeyemo, M.D.

Dr. Adebowale Adeyemo is an associate investigator and deputy director of Nhgri's Center for Research on Genomics and Global Health.
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Identification of factor H-like protein 1 as the predominant…

The tight regulation of innate immunity on extracellular matrix (ECM) is a vital part of immune homeostasis throughout the human body and disruption to this regulation in the eye is thought to contribute directly to the progression of age…
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Induction of fibroblast senescence generates a non-fibrogenic…

Cancer-associated fibroblasts (CAF) remain a poorly characterized, heterogeneous cell population. Here we characterized two previously described tumor-promoting CAF sub-types, smooth muscle actin (SMA)-positive myofibroblasts and senescent…
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