Cellular DNA replication requires efficient copying of the double-stranded chromosomal DNA. The leading strand is elongated continuously in the direction of fork opening, whereas the lagging strand is made discontinuously in the opposite…
Read 3,450 reviews from the world’s largest community for readers. With this outrageous new novel, China Miéville has written one of the strangest, funnies…
Long interspersed elements 1 (LINE-1) occupy at least 17% of the human genome and are its only active autonomous retrotransposons. However, the host factors that regulate LINE-1 retrotransposition are not fully understood.
Shyamal Peddada is a Senior Investigator who leads the Constrained Statistical Inference Group within the Biostatistics and Computational Biology Branch.
The decision by a cell to enter a round of growth and division must be intimately coordinated with nutrient availability and its metabolic state. These metabolic and nutritional requirements, and the mechanisms by which they induce cell…
The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. [1 ] [2 ] [3 ] They are estimated to constitute 1% of all described fungal species. [4 ]
Growing evidence suggests that microRNAs coordinate various biological processes in the liver. We describe experiments to address the physiological roles of these new regulators of gene expression in the liver that are as of yet largely…