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Random GFP∷cDNA fusions enable visualization of subcellular…
We describe a general approach for identifying components of subcellular structures in a multicellular organism by exploiting the ability to generate thousands of independent transformants in Arabidopsis thaliana.
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Common Pathogenic Effects of Missense Mutations in the P-Type…
Mutations in the ATP13A2 gene (PARK9) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome (KRS), a neurodegenerative disease characterized by parkinsonism. KRS mutations produce truncated forms of ATP13A2 with impaired protein…
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The dynamic interaction of Ambra1 with the dynein motor complex…
When autophagy is induced, ULK1 phosphorylates Ambra1, releasing the autophagy core complex from the cytoskeleton and allowing its relocalization to the ER membrane to nucleate autophagosome formation.
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Insulin/IGF-1 and Hypoxia Signaling Act in Concert…
RNAi of 28 genes further increased expression of the Pftn-1:gfp reporter (Table S2), already induced by daf-2(m577). Of note was the large increase in expression upon RNAi of unc-62, a transcription factor with a conserved role in ferritin…
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ER-mitochondria contacts couple mtDNA synthesis with…
Mitochondrial DNA (mtDNA) encodes RNAs and proteins critical for cell function. In human cells, 100–1000s mtDNA copies are replicated asynchronously, packaged into protein-DNA nucleoids, and distributed within a dynamic mitochondrial…
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Evolved Cas9 variants with broad PAM compatibility and high DNA…
A key limitation to the use of Crispr-Cas9 proteins for genome editing and other applications is the requirement that a protospacer adjacent motif (PAM) be present at the target site.
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Yoshihiro Ozeki | Tokyo University of Agriculture and…
Yoshihiro Ozeki | Cited by 6,532 | of Tokyo University of Agriculture and Technology, Tokyo (TUAT) | Read 217 publications | Contact Yoshihiro Ozeki
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Afaf S. Fahmy's research works | NSF National Center for…
Afaf S. Fahmy's 65 research works with 1,285 citations, including: Purification and characterization of cationic peroxidase from ginger (Zingiber officinale)
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BLMP-1/Blimp-1 Regulates the Spatiotemporal Ce…
Published in the journal: . PLoS Genet 10(6): e32767. doi:10.1371/journal.pgen.1004428 Category: Research Article doi: https://doi.org/10.1371/journal.pgen.1004428
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