The purpose of our study was to better understand the relationship between mitochondrial structural proteins, particularly dynamin-related protein 1 (Drp1) and amyloid beta (Aβ) in the progression of Alzheimer's disease (AD).
Premiere Networks, Inc. (formerly Premiere Radio Networks, shortened as PRN) is an American media company, a subsidiary of iHeartMedia, for which it currently serves as its main original radio content distribution and production arm.
PINK1, a mitochondrial serine/threonine kinase, is the product of a gene mutated in an autosomal recessive form of Parkinson disease. PINK1 is constitutively degraded by an unknown mechanism and stabilized selectively on damaged…
El diseño de mundo abierto permite a los jugadores recorrer libremente Liberty City, que consta de tres islas principales, y el estado vecino de Alderney, inspirado en Nueva Jersey.
Environmental factors are poorly understood in the etiology of Alzheimer’s Disease and related dementias (AD). The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in…
The worldwide prevalence of metabolic diseases, including obesity and diabetes, is increasing. Mitochondrial dysfunction is recognized as a core feature of these diseases. Emerging evidence also suggests that defects in mitochondrial…
Here, we present Perturb-Multimodal (Perturb-Multi), a paired imaging and sequencing method to construct large-scale, multimodal genotype-phenotype maps in tissues with pooled genetic perturbations.