Gene expression can be modulated by chromatin changes induced by histone acetylation and deacetylation. Acetylation of histone lysine residues by acetyltransferases is associated with transcriptionally active chromatin, whereas the removal…
Environmental factors are poorly understood in the etiology of Alzheimer’s Disease and related dementias (AD). The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in…
In chronic myelogenous leukemia, reciprocal translocation between chromosome 9 and chromosome 22 generates a chimeric protein, Bcr-Abl, that leads to hyperactivity of tyrosine kinase-linked signaling transduction.
Fig. 4. TLS and template switching are redundant in promoting rad27Δ viability. TLS and template switching are redundant in promoting rad27Δ viability. (A and B) 10-fold serial dilutions of the indicated strains were incubated 1.5 or 2.5…
The sea slug Elysia chlorotica acquires plastids by ingestion of its algal food source Vaucheria litorea. Organelles are sequestered in the mollusc's digestive epithelium, where they photosynthesize for months in the absence of algal
Perinatal hypoxic‐ischaemic injury (HII) is a significant cause of neurodevelopmental impairment and disability. Studies employing 31P magnetic resonance spectroscopy to measure phosphorus metabolites in situ in the brains of newborn…
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