Material para ser utilizado en cursos iniciales de capacitación en wayuunaiki. Cada capítulo está seguido por ejercicios de aplicación de los análisis presentados. Fue preparado para ser utilizado en cursos promovidos por la organización…
Activation of colonic proteinase-activated receptor-2 (PAR2) caused inflammation and increased mucosal permeability in mouse colon. The present study was aimed at characterizing the possible links between these two phenomena.
My background is in molecular genetics, signal transdcution, cancer. Current activities include making sense of high-throughput omics data in the sphere of translational bioinformatics.
Stem and progenitor cells utilize asymmetric cell divisions to balance proliferation and differentiation. Evidence from lower eukaryotes shows that this process is regulated by proteins asymmetrically distributed at the cell cortex during…
Poly-ADP-ribose polymerases (Parps) use NAD+ as substrate to generate polymers of ADP-ribose. We targeted the catalytic domain of human PARP1 as molecular NAD+ detector into cellular organelles.