Hedgehog signalling—an essential pathway during embryonic pancreatic development, the misregulation of which has been implicated in several forms of cancer—may also be an important mediator in human pancreatic carcinoma1–8.
Within each block of 100 kb, the diversity of every functional element (according to the recent gene annotations in OGSv3.2; [80]) was independently capped at θw≈0.002 by randomly subsampling the SNPs, resulting in a thinned dataset…
Conversion of the primary bile acids cholic acid (CA) and chenodeoxycholic acid (CDCA) to the secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA) is performed by a few species of intestinal bacteria in the genus…
Since the focus of our study is the Neolithic transition, we restrict our analysis of Y-chromosomes and rainfall to the approximate Fertile Crescent ‘homeland’ region implicated in the shift to an agro-pastoralist economy.
Aging is a biological process that affects most cells, organisms and species. Telomeres have been postulated as a universal biological clock that shortens in parallel with aging in cells.