Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs…
Controlling osteoclastogenesis is critical to maintain physiological bone homeostasis and prevent skeletal disorders. Although signaling activating nuclear factor of activated T cells 1 (Nfatc1), a transcription factor essential for
Pericardial fat is a localized fat depot associated with coronary artery calcium and myocardial infarction. We hypothesized that genetic loci would be associated with pericardial fat independent of other body fat depots.
Cytokine signaling pathways play a central role in the pathogenesis of inflammatory bowel disease (IBD). Ulcerative colitis (UC) and Crohn’s disease (CD) have unique as well as overlapping phenotypes, susceptibility genes, and gene…
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30. 11. 2023On National Computer Security Day, we express our sincere appreciation for the invaluable work of FBI Cyber Division For over two decades, the Bureau's Cyber Division and Internet Crime Complaint Center (IC3) have been the ultimate…