Leptin Targets in the Mouse Brain - PMC

The central actions of leptin are essential for homeostatic control of adipose tissue mass, glucose metabolism, and many autonomic and neuroendocrine systems. In the brain, leptin acts on numerous different cell types via the long-form…
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The Inhibition of TDP-43 Mitochondrial Localization Blocks Its…

Genetic mutations in TAR DNA-binding protein 43 (TDP-43) cause amyotrophic lateral sclerosis (ALS), and the increased presence of TDP-43 in the cytoplasm is a prominent histopathological feature of degenerating neurons in various…
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Nerves Regulate Cardiomyocyte Proliferation and Heart…

Some organisms, such as adult zebrafish and newborn mice, have the capacity to regenerate heart tissue following injury. Unraveling the mechanisms of heart regeneration is fundamental to understanding why regeneration fails in adult humans…
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Biofilm - Wikipedia

Aggregate of microorganisms in which cells that are frequently embedded within a self-produced matrix of extracellular polymeric substances (EPSs) adhere to each other and/or to a surface.
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A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain…

These results, together with SCope, allow comprehensive exploration of all transcriptional states of an entire aging brain.
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The zinc-finger transcription factor Klf4 is required for…

Klf4 (formerly GKLF) is a zinc-finger transcription factor expressed in the epithelia of the skin, lungs, gastrointestinal tract and several other organs. In vitro studies have suggested that Klf4 plays an important role in cell…
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Nutrient status shapes selfish mitochondrial genome dynamics…

Food supply and nutrient stress tolerance coordinately shape the multilevel selection dynamics of a mitochondrial cheater by promoting cheater persistence at both within-host and between-host levels of selection.
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Single-cell transcriptomes and whole-brain projections of…

The combination of single-cell transcriptomics and whole-brain mapping of bulk and single-cell projections reveals the relationship between the molecular architecture, cell body distribution, and axonal arborization of serotonin neurons.
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File Extentions

The Rocky Mountain WebBackup service is a complete, automated internet backup service for your PC, using state-of-the-art enterprise backup software.
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