Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to…
Frost et al demonstrate that low concentrations of iron in serum, caused by the hormone hepcidin, inhibit the body’s response to vaccines and infections; conversely, increasing iron can boost immunity.
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The Coagulation and Immune Systems Are Directly Linked through…
Surface pro-IL-1α on macrophages and activated platelets was cleaved and activated by thrombin, while tissue factor, a potent thrombin activator, colocalized with pro-IL-1α in the epidermis.
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Murine model of colonization with fungal pathogen Candida auris…
Candida auris is an emerging multi-drug resistant human fungal pathogen. C. auris skin colonization results in environmental shedding, which underlies hospital transmissions, and predisposes patients to subsequent infections.
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Electronic, Aviation and NSN Parts Avaiable For Quote 4140-01…
Quote Today For NSN, Electronic & Aviation Parts 4140-01-483-7867 C26206 , 5940-00-080-5666 JN113062-405 , 1660-00-589-2471 M88A92 .
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Intestinal barrier dysfunction plays an integral role in…
Evidence suggests an important role for gut-microbiota dysbiosis in the development of rheumatoid arthritis (RA). The link between changes in gut bacteria and the development of joint inflammation is missing.
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Unique properties of thymic antigen-presenting cells promote…
Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use.
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Cytotoxic T-Lymphocyte Epitope Vaccination Protects against…
Human metapneumovirus (hMPV) has emerged as an important human respiratory pathogen causing upper and lower respiratory tract infections in young children and older adults. In addition, hMPV infection is associated with asthma exacerbation…
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Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A…
Idiopathic pulmonary fibrosis (IPF) is a destructive inflammatory disease with limited therapeutic options. To better understand the inflammatory responses that precede and concur with collagen deposition, we used three models of pulmonary…
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SharePoint Bloggers: 2022
Mark Kruger, SharePoint MVP, iImagineIT Inc., Florida SharePoint Consulting, SharePoint Blog, Office 365, Knowledge Management, SharePoint Architect
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Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T…
Here, we uncovered GSL biosynthesis as a critical glucose-dependent pathway essential for CD8+ T cell expansion and cytotoxic function.
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