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Comprehensive molecular portraits of human breast tumors - PMC
We analyzed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, mRNA arrays, microRNA sequencing and reverse phase protein arrays. Our ability to integrate information across platforms provided key…
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Archana Nagaraja | Research scientist | University of Texas MD…
Archana Nagaraja, Research scientist | Cited by 3,993 | of University of Texas MD Anderson Cancer Center, Houston (MD Anderson) | Read 97 publications | Contact Archana Nagaraja
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Jin-Soo KIM | Seoul National University, Seoul | SNU…
Jin-Soo KIM | Cited by 29,351 | of Seoul National University, Seoul (SNU) | Read 283 publications | Contact Jin-Soo KIM
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A CDK11-dependent RNA polymerase II pause-checkpoint precedes…
In this study, we propose a critical role for CDK11 in the Pol II pausing-to-elongation transition at a checkpoint that precedes and is independent from CDK9. Selective CDK11 inhibition or degradation results in acute ablation of RNA…
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High IGF-IR activity in triple-negative breast cancer cell…
We previously reported an IGF gene expression signature, based upon genes induced or repressed by IGF-I, which correlated with poor prognosis in breast cancer. We tested if the IGF signature was affected by anti-IGF-IR inhibitors, and if…
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Role of the Umo Proteins and the Rcs Phosphorelay in the…
Proteus mirabilis is a Gram-negative bacterium that exists as a short rod when grown in liquid medium, but during growth on surfaces it undergoes a distinct physical and biochemical change that culminates in the formation of a swarmer cell…
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Integrative Analysis Identifies Four Molecular and Clinical…
We report change-of-function SRSF2 mutations. Within D3-UM, EIF1AX- and SRSF2/SF3B1-mutant tumors have distinct somatic copy number alterations and DNA methylation profiles, providing insight into the biology of these low- versus…
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A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000…
Here, we present the detection and characterization of a large number of expressed enhancers in a genome-wide analysis of 8928 tumor samples across 33 cancer types using TCGA RNA-seq data.
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F. Severo Ochoa - Organización
El Patronato está constituido por un mínimo de seis y un máximo de doce miembros que adoptarán sus acuerdos por mayoría en los términos establecidos en sus Estatutos.
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Equilibrative Nucleoside Transporters – Regulation of JAK-STAT…
Individual primer for fibronectin 1 and collagen I had been the next: forwards, 5-Ccgtgggcaactctgtc-3, and invert 5-Tgcggcagttgtcacag-3, and forwards, 5-Tgacgagaccaagaactg-3, and invert 5-Ccatccaaaccactgaaacc-3, respectively.
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