Although epidemiological data have indicated that a strong negative association exists between coffee consumption and the prevalence of obesity-associated diseases, the molecular mechanisms by which coffee intake prevents obesity-associated…
Mutations in the WNK [with no lysine (K) kinase] family instigate hypertension and pain perception disorders. Of the four WNK isoforms, much of the focus has been on WNK1, which is activated in response to osmotic stress by phosphorylation…
The unfolded-protein response (UPR) of the endoplasmic reticulum (ER) has been linked to oxidant production, although the molecular details and functional significance of this linkage are poorly understood.
The NCAA Division I Football Championship is an annual post-season college football game, played since 2006, used to determine a national champion of the NCAA Division I Football Championship Subdivision (FCS).
Atherosclerosis is a complex disease that includes several events, including reactive oxygen species (ROS) stress, inflammation, endothelial dysfunction, lipid deposition, and vascular smooth muscle cell (VSMC) proliferation and migration…
Andrew Bennett currently works at the School of Life Sciences, University of Nottingham. Andrew does research in Molecular Biology, Systems Biology and Human Biology. His current research focuses on developing human tissue models of disease…
During meiosis, the germline nucleus undergoes extensive reorganization to accurately align homologous chromosomes along their entire length, enabling them to recombine and ultimately segregate from one another.
Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second deadliest cancer by 2030. Advances in therapeutic treatments are urgently required to fight against this fatal disease.