Heigo is dé specialist in de ontwikkeling, productie en verkoop van hoogwaardige werkkleding en persoonlijke beschermingsmiddelen (pbm's). De dienstverlening richt zich op specifieke behoeftes en het ontzorgen van klanten.
Large-scale surveys of single-cell gene expression have the potential to reveal rare cell populations and lineage relationships, but require efficient methods for cell capture and mRNA sequencing1–4.
Cholesterol is an essential lipid in vertebrates, but excess blood cholesterol promotes atherosclerosis. In the liver, cholesterol is metabolized to bile acids by cytochrome P450, family 7, subfamily a, polypeptide 1 (CYP7A1), the…
Nicotine has many effects on CNS functions, presumably through its action on neuronal nicotinic acetylcholine receptors (AChRs). One subclass of AChRs that binds the snake venom toxin α-bungarotoxin (α-Bgt-AChRs) has been shown to modulate…
Hair follicles are simple, accessible models for many developmental processes. Here, using mutant mice, we show that Bmpr2, a known receptor for bone morphogenetic proteins (Bmps), and Acvr2a, a known receptor for Bmps and activins, are…
Increased plasminogen activator inhibitor-1 (PAI-1) levels are associated with a number of pathophysiological complications; among them is obesity. Resveratrol was proposed to improve obesity-related health problems, but the effect of…
In lower eukaryotes, Sir2 serves as a histone deacetylase and is implicated in chromatin silencing, longevity and genome stability. Here we mutated the SIRT1 gene, a homolog of yeast Sir2, in mice to study its function.
Juli um 1t,36 Uhr auf die letzte Pendelfahrt zum Schul¬ zentrum Tailfingen, Oie Drei von der Tal¬ gangbahn: Lokführer Günther Schuh, Betriebs¬ leiter Klaus Bosch und Wolf gang Göz (vT) am 29.7, in Onstmettingen.