I focussed my research efforts on two major topics: nutrigenomic and signaling events taking place under L-carnitine deficiency and subsequent supplementation and generation of superactive human thymidine kinase 1 (TK1) mutants and their…
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30,000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4…
We showed previously that wild-type mice primed via intranasal inoculation with live or heat-inactivated Lactobacillus species were fully (100%) protected against the lethal sequelae of infection with the virulent pathogen, pneumonia virus…
Alström syndrome is a rare autosomal recessive genetic disorder characterized by cone-rod dystrophy, hearing loss, childhood truncal obesity, insulin resistance and hyperinsulinemia, type 2 diabetes, hypertriglyceridemia, short stature in…
The microtubule-binding 63-kDa cytoskeleton-linking membrane protein (Climp-63) is an integral membrane protein that links the endoplasmic reticulum (ER) to microtubules. Here, we tested whether th.