Immune homeostasis is dependent on tight control over the size of a population of regulatory T (Treg) cells capable of suppressing over-exuberant immune responses. The Treg cell subset is comprised of cells that commit to the Treg lineage…
Donald Court | Cited by 10,755 | of National Cancer Institute (USA), National Institutes of Health, Bethesda (NCI) | Read 123 publications | Contact Donald Court
BRCA1—a breast and ovarian cancer suppressor gene—promotes genome integrity. To study the functionality of BRCA1 in the heterozygous state, we established a collection of primary human BRCA1+/+ and BRCA1mut/+ mammary epithelial cells and…
There are at least 14 different renal tubule segments, each with characteristic cell types with distinct functions. Although the advent of RNA sequencing (RNA-seq) has greatly improved our understanding of gene expression in these renal…
Mitochondria are highly mobile and dynamic organelles that continually fuse and divide. These processes allow mitochondria to exchange contents, including mitochondrial DNA (mtDNA).
My research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of my career, I have made important contributions to our understanding of mammalian heart regeneration and I…
Dilated cardiomyopathy (DCM) is defined by progressive functional and structural changes. We performed RNA-seq at different stages of disease to define molecular signaling in the progression from pre-DCM hearts to DCM and overt heart…
Halle, 9o3. Abriss der urgermanischen Lautlehre. Strassburg, 894. tot,atsder, Alois. Zur Lauflêhre der griechischen, lateinischen und romanischen Lehnw6rter ira Altenglischen.