Primera División (v překladu První liga), obecně známá také jako La Liga (pod sponzorským názvem jako Laliga EA Sports) je nejvyšší španělská fotbalová soutěž.
Lifespan extension induced by germline ablation in C. elegans is regulated by the nuclear hormone receptor NHR-80 in a process that requires the production of oleic acid by activation of the lipid desaturase FAT-6/SCD1.
The Caenorhabditis elegans Nuclear Hormone Receptor NHR-49 coordinates expression of fatty acid (FA) metabolic genes during periods of feeding and in response to fasting. Here we report the identification of MDT-15, a subunit of the C.
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My research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of my career, I have made important contributions to our understanding of mammalian heart regeneration and I…
Determining the precise mechanisms whereby such specificity arises and how networks nevertheless remain flexible in responding to environmental and physiological fluctuations is an interesting challenge.
The induction of ftn-1 levels by iron requires a 63 bp element (the iron-dependent element, or IDE) in the gene's promoter [20]. We wondered whether the hif-1 pathway might mediate the effects of iron on IDE-mediated gene expression.
We identified 1,175 genomic regions to be bound in vivo by DAF-12, and these regions are enriched in known DAF-12 binding motifs and act as DAF-12 response elements in transfected cells and in transgenic worms.