Andrew Lackner, Professor of Microbiology, Immunology and Pathology | Cited by 29,314 | of Tulane University, New Orleans (TU) | Read 378 publications | Contact Andrew Lackner
At the forefront of nanotechnology R&D, my work revolutionises materials application in… · Experience: Hanano Materials technology · Education: University of Bath · Location: Godmanchester · 500+ connections on LinkedIn.
Class switch recombination (CSR) is a DNA recombination process that replaces the immunoglobulin (Ig) constant region for the isotype that can best protect against the pathogen. Dysregulation of CSR can cause self-reactive BCRs and B cell…
Mohamad Karimi, Associate Professor | Cited by 2,700 | of Shiraz University of Medical Sciences, Shiraz (SUMS) | Read 185 publications | Contact Mohamad Karimi
We studied germinal center responses and HIV-1 antibody development in rhesus macaques (RMs) immunized with sequential CH505 gp120 envelopes (Envs), with or without anti-CD25 monoclonal antibody (mAb).
This study assessed immune responses in mice following ground-based, simulated deep spaceflight conditions, compared with data from astronauts on International Space Station missions.
Germinal centers (GCs) are the primary sites of clonal B cell expansion and affinity maturation, directing the production of high-affinity antibodies. This response is a central driver of pathogenesis in autoimmune diseases, such as…