The dopamine receptor antagonist trifluoperazine prevents…

GBM is the most deadly adult brain cancer. The current standard-of-care is surgery followed by RT and temozolomide, which results in a median survival time of only 15 mo. The efficacy of chemotherapies and targeted therapies in GBM is very…
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Essential and recurrent roles for hairpin RNAs in silencing de…

Jeffrey Vedanayagam1, Marion Herbette2, Holly Mudgett3, Ching-Jung Lin1,4, Chun- Ming Lai1, Caitlin McDonough-Goldstein5, Stephen Dorus5, Benjamin Loppin2, Colin Meiklejohn3, Raphae¨lle Dubruille2, Eric C.
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Measurement of Plasma Cell-Free Mitochondrial Tumor DNA…

These findings show that detection of tumor mitochondrial DNA is more sensitive than circulating tumor DNA analysis to detect and monitor tumor burden in
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