GBM is the most deadly adult brain cancer. The current standard-of-care is surgery followed by RT and temozolomide, which results in a median survival time of only 15 mo. The efficacy of chemotherapies and targeted therapies in GBM is very…
Jeffrey Vedanayagam1, Marion Herbette2, Holly Mudgett3, Ching-Jung Lin1,4, Chun- Ming Lai1, Caitlin McDonough-Goldstein5, Stephen Dorus5, Benjamin Loppin2, Colin Meiklejohn3, Raphae¨lle Dubruille2, Eric C.
These findings show that detection of tumor mitochondrial DNA is more sensitive than circulating tumor DNA analysis to detect and monitor tumor burden in