Revolución francesa - Wikipedia, la enciclopedia libre
La Revolución francesa [2 ] (en francés: Révolution française) fue un conflicto social y político, con diversos periodos de violencia, que convulsionó la Francia del Antiguo Régimen, y a otros países por extensión de sus implicaciones.
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H. Leighton Grimes | Professor (Full) | PhD | Cincinnati…
I have a broad background in hematopoiesis, molecular biology, and molecular oncology including mouse modeling of hematopoiesis, myelopoiesis, marrow failure syndromes and leukemia.
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Telomerase modulates Wnt signalling by association with target…
Stem cells are controlled, in part, by genetic pathways frequently dysregulated during human tumorigenesis. Either stimulation of Wnt/β-catenin signalling or overexpression of telomerase is sufficient to activate quiescent epidermal stem…
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Human ES cell-derived neural rosettes reveal a functionally…
Neural stem cells (NSCs) yield both neuronal and glial progeny, but their differentiation potential toward multiple region-specific neuron types remains remarkably poor. In contrast, embryonic stem cell (ESC) progeny readily yield region…
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TopBP1 Governs Hematopoietic Stem/Progenitor Cells…
Impairment of these pathways could lead to the progressive bone marrow failure (BMF) and hematopoietic malignancies. Here we reported a novel function of topoisomerase II β binding protein 1 (TopBP1) in definitive hematopoiesis through…
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Hedgehog signalling is essential for maintenance of cancer stem…
Although the role of Hedgehog (Hh) signalling in embryonic pattern formation is well established1, its functions in adult tissue renewal and maintenance remain unclear, and the relationship of these functions to cancer development has not…
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β-Catenin Is Required for the Tumorigenic Behavior of Triple…
Our previous data illustrated that activation of the canonical Wnt signaling pathway was enriched in triple-negative breast cancer and associated with reduced overall survival in all patients.
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Wnt10b Deficiency Promotes Coexpression of Myogenic and…
Adult myoblasts retain plasticity in developmental potential and can be induced to undergo myogenic, adipogenic, or osteoblastogenic differentiation in vitro. In this report, we show that the balance between myogenic and adipogenic…
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