Está ubicado en el extremo noroeste del país, limitando al norte con el océano Ártico, [7 ] [8 ] [9 ]al este con Territorios del Noroeste, al sur con Columbia Británica [10 ] [11 ]y al oeste con Alaska [12 ] [13 ] (Estados Unidos). [14…
Microglial-mediated neuroinflammation plays an important role in vascular dementia, and modulating neuroinflammation has emerged as a promising treatment target. Nicotinamide adenine dinucleotide (NAD+) shows anti-inflammatory and anti…
Cryo-electron microscopy (cryo-EM) is increasingly becoming a mainstream technology for studying the architecture of cells, viruses and protein assemblies at molecular resolution. Recent developments in microscope design and imaging…
Microglia are considered the resident immune cells of the central nervous system (CNS). In response to harmful stimuli, an inflammatory reaction ensues in which microglia are activated in a sequenced spectrum of pro- and antiinflammatory…