Alström Syndrome: Genetics and Clinical Overview - PMC
Alström syndrome is a rare autosomal recessive genetic disorder characterized by cone-rod dystrophy, hearing loss, childhood truncal obesity, insulin resistance and hyperinsulinemia, type 2 diabetes, hypertriglyceridemia, short stature in…
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Tryptophan deprivation sensitizes activated T cells to…
Cells expressing indoleamine 2,3-dioxygenase (IDO), an enzyme which catabolizes tryptophan, prevent T-cell proliferation in vitro, suppress maternal antifetal immunity during pregnancy and inhibit T-cell-mediated responses to tumour…
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CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct…
CTLA-4 and PD-1 are receptors that negatively regulate T-cell activation. Ligation of both CTLA-4 and PD-1 blocked CD3/CD28-mediated upregulation of glucose metabolism and Akt activity, but each accomplished this regulation using separate…
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The dietary isothiocyanate sulforaphane modulates gene…
Dietary or therapeutic interventions to counteract the loss of PTEN expression could contribute to the prevention of prostate carcinogenesis or reduce the rate of cancer progression.
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Psoriasis - Wikipedia
Psoriasis is classified as a papulosquamous disorder and is most commonly subdivided into different categories based on histological characteristics. [3 ] [10 ] Variants include plaque, pustular, guttate, and flexural psoriasis.
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Padmanee Sharma | MD Anderson Cancer Center
Padmanee Sharma, M.D., Ph.D., Department of Genitourinary Medical Oncology, Division of Cancer Medicine
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Alteration of Gut Microbiota and Inflammatory Cytokine…
Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-fluorouracil (5-Fu) induced mucositis. However, current knowledge of the overall profiles of 5-Fu-disturbed gut microbiota is limited, and so far…
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The Benefits of the Mediterranean Diet on Inflamm-Aging in…
(1) Background: Numerous elements of the Mediterranean diet (MD) have antioxidant and anti-inflammatory qualities. (2) Methods: We present a narrative review of the potential benefits of the Mediterranean dietary pattern (MD) in mitigating…
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Conventional Cancer Treatment | IntechOpen
Open access peer-reviewed chapter
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EurekaMag Full Text Articles Chapter 51176
Full Text Articles available from EurekaMag Chapter 51176
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