Loss of Nat4 and its associated histone H4 N‐terminal…

Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary interventions with specific…
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Hajime Ogino | Professor, Director of Amphibian Research Center…

Hajime Ogino, Professor, Director of Amphibian Research Center | Cited by 3,611 | of Hiroshima University, Hiroshima (HU) | Read 101 publications | Contact Hajime Ogino
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Manika Bhadra | Research profile

Manika Bhadra | Cited by 3,223 | | Read 131 publications | Contact Manika Bhadra
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Sylvester Johnson Jr. – Business Owner | LinkedIn

Business Owner · I have been in the computer field for over 50 years in both military and civilian capacities. During that time, I have worked in every area of the computer field: Computer Operations, Tech Support, Security, Programming…
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Sex-Related Differences in Gene Expression in Human Skeletal…

There is sexual dimorphism of skeletal muscle, the most obvious feature being the larger muscle mass of men. The molecular basis for this difference has not been clearly defined. To identify genes that might contribute to the relatively…
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Wolfram Knoefel | Heinrich Heine University Düsseldorf…

Wolfram Knoefel | Cited by 17,630 | of Heinrich Heine University Düsseldorf, Düsseldorf (HHU) | Read 1047 publications | Contact Wolfram Knoefel
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The impact of cellular metabolism on chromatin dynamics and…

The substrates used to modify nucleic acids and chromatin are affected by nutrient availability and the activity of metabolic pathways. Thus, cellular metabolism constitutes a fundamental component of chromatin status and thereby of genome…
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Integrated analysis of multimodal single-cell data - PMC

The simultaneous measurement of multiple modalities represents an exciting frontier for single-cell genomics and necessitates computational methods that can define cellular states based on multimodal data.
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Normal DNA Methylation Dynamics in Dicer1-Defi…

Dicer1-deficient mouse ES cells have often been found to be deficient in DNA methylation. These observations have been predominantly of localized and dispersed repeats which constitute the large majority of methylated CpG dyads in the…
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Site-Specific Silencing of Regulatory Elements as a Mechanism…

The data support a model whereby inactivation of specific regulatory elements, rather than a simple chromosome-wide separation from transcription machinery, governs gene silencing over the Xi.
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