Here, we show that a CDRH3-dominated anti-CD4-BS bNAb, CH103, establishes quaternary interaction despite regular-length FRH3 and CDRH1. This quaternary interaction is critical for neutralization and is primarily mediated by two FRH3 acidic…
Published in the journal: . PLoS Genet 10(9): e32767. doi:10.1371/journal.pgen.1004599 Category: Research Article doi: https://doi.org/10.1371/journal.pgen.1004599
Abstract The Sand Mountain and Lookout Mountain Plateaus in northeastern Alabama have been established as a regional relative maximum in tornadogenesis reports within the southeastern United States.
Prior studies have shown that disruption of mitochondrial electron transport chain (ETC) function in the nematode Caenorhabditis elegans can result in life extension. Counter to these findings, many mutations that disrupt ETC function in…