In their seminal publication describing the structure of the DNA double helix1, Watson and Crick wrote what may be one of the greatest understatements in the scientific literature, namely that “It has not escaped our notice that the…
Nausea and vomiting are common experiences in pregnancy, affecting 70–80% of all pregnant women. Although most women with nausea and vomiting of pregnancy (NVP) have symptoms limited to the first trimester, a small percentage of women have a…
They are also pivotal in summarizing existing research to guide future studies, thereby cementing their role as a fundamental methodology in metascience.
Candida is the shortened name used to describe a class of fungi that includes more than 150 species of yeast. In healthy individuals, Candida exists harmlessly in mucus membranes such as your ears, eyes, gastrointestinal tract, mouth, nose…
Targeted gene regulation on a genome-wide scale is a powerful strategy for interrogating, perturbing, and engineering cellular systems. Here, we develop a method for controlling gene expression based on Cas9, an RNA-guided DNA endonuclease…