02EBE032-CCF1-4FC1-A28E-FD67C2723226_1_105_c | Tgacv
Střední škola technická, gastronomická a automobilní, Chomutov, příspěvková organizace
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CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T…
Immune checkpoint blockade, exemplified by antibodies targeting the programmed death-1 (PD-1) receptor, can induce durable tumor regressions in some patients. To enhance the efficacy of existing immunotherapies, we screened for small…
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A CDK11-dependent RNA polymerase II pause-checkpoint precedes…
In this study, we propose a critical role for CDK11 in the Pol II pausing-to-elongation transition at a checkpoint that precedes and is independent from CDK9. Selective CDK11 inhibition or degradation results in acute ablation of RNA…
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EMF1 and PRC2 Cooperate to Repress Key Regulators…
EMF1 interacts with regulatory genes, which are silenced to allow vegetative growth, and with genes specifying cell fates during growth and differentiation.
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Correlation between CDK1 protein and CDK1 mRNA during oocyte…
The aim of this study was to investigate the correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in vivo in mouse. GV, GVBD, MI and MII oocytes were obtained from mice, respectively.
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Crispr/Cas9-based Editing of CDK4, p107, and TGFβ1 in Human…
The Crispr/Cas9 system is considered one of the most controversial yet powerful genome-editing tool with high potentiality and wide-angled array of biomedical applications. Cancer is considered one of the serious health-threat diseases that…
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Rad52 recruitment is DNA replication independent and regulated…
Recruitment of the homologous recombination machinery to sites of double-strand breaks is a cell cycle-regulated event requiring entry into S phase and CDK1 activity. Here, we demonstrate that the central recombination protein, Rad52, forms…
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MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK…
MiR-191 expression is upregulated in senescencent human epidermal keratinocytes. miR-191 overexpression is sufficient per se to induce senescence in keratinocytes. SATB1 and CDK6 are downregulated in senescence and are direct miR-191…
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Comprar Hydroxyzine 25mg, 10mg Sin Receta En Farmacia Vall…
Naší specialitou jsou komerční vystoupeni, maturitní nástupy, kurzy v MŠ a ZŠ
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Revealing the Mechanism of In Vitro Wound Healing Properties of…
In the present investigation, we examined the effect of Hyuganatsu (Citrus tamurana) extract (HE) on skin fibroblast (TIG-119) proliferation and migration during in vitro wound healing.
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