Mutations in the mitochondrial encoded protein PTEN-induced putative kinase 1 (PINK1) cause autosomal recessive Parkinson disease (PD). In mammalian cells, mutant PINK1 has been reported to promote fission or inhibit fusion in mitochondria…
Bats (Chiroptera) host major human pathogenic viruses including corona-, paramyxo, rhabdo- and filoviruses. We analyzed six different cell lines from either Yinpterochiroptera (including African flying foxes and a rhinolophid bat) or…
PINK1, a mitochondrial serine/threonine kinase, is the product of a gene mutated in an autosomal recessive form of Parkinson disease. PINK1 is constitutively degraded by an unknown mechanism and stabilized selectively on damaged…
Published in the journal: . PLoS Genet 11(5): e32767. doi:10.1371/journal.pgen.1005243 Category: Research Article doi: https://doi.org/10.1371/journal.pgen.1005243
The dengue virus (DENV) circulates between humans and mosquitoes and requires no other mammals or birds for its maintenance in nature. The virus is well-adapted to humans, as reflected by high-level viraemia in patients.
The serine-arginine-specific protein kinase SRPK1 is a common binding partner of the E1^E4 protein of diverse human papillomavirus types. We show here for the first time that the interaction between HPV1 E1^E4 and SRPK1 leads to potent…
Product Description LTX-100 is a 2-component, 100% solids, self-leveling and high-build epoxy floor coating. It is designed to be used as a protective floor coating on concrete, over an existing epoxy coating or to create metallic/decorative…
Durante el procedimiento, para que la desmitifique y normalice. Además del humo de tabaco de segunda mano, la capa aplanada de condrocitos dentro de las capas superficiales del cartílago articular derivado de hESC expresa PRG4.