These receptors form homo- and heterodimeric complexes and signal to kinase cascades and scaffold a variety of proteins.The authors discuss classic mechanisms and developments in understanding opioid tolerance and opioid receptor signaling…
Acute inflammation is a key component of the immune system’s response to pathogens, toxic agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing pathogenic factors and restoring tissue homeostasis.
Sitz des Fußball-Verband Westfalen ist seit 1951 die Sportschule Kaiserau in Kamen, vorher saß der Verband in Hamm. [3 ] Der FLVW entstand im Jahre 1954 durch den Zusammenschluss des im Jahre 1946 gegründeten Fußball-Verband Westfalen und…
Functional interactions between the G protein-coupled dopamine D1 and histamine H3 receptors have been described in the brain. In the present study we investigated the existence of D1–H3 receptor heteromers and their biochemical…
Dansyl-X, SE is an environmentally sensitive hydrophobic dye (Excitation 333 nM; Emission 518 nM). Dansyl-X, SE can increase fluorescence intensity in hydrophobic environment. - Mechanism of Action & Protocol.
Carbohydrates are an important component of the diet. The carbohydrates that we ingest range from simple monosaccharides (glucose, fructose and galactose) to disaccharides (lactose, sucrose) to complex polysaccharides.
Protein kinase A-driven increases in c-MYC protein expression and tumor cell proliferation can be blocked by eIF4A inhibitors, suggesting a potential new treatment option for patients with oncogenic PKA activation.
AMP-activated protein kinase (AMPK) has emerged as a key regulator of energy metabolism in the heart. The high energy demands of the heart are primarily met by the metabolism of both fatty acids and glucose, both processes being regulated…