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In the binding of the peptide Pi4 to the Kv1.2 channel, the β-sheet structure is thought to play an important role. First, the residue 35Y, located in the β-sheet structure, tightly interacts via electrostatic forces with the aromatic…
It acts as a monomer. The toxin belongs to the type 2 sea anemone peptides targeting voltage-gated K channels. Other type 2 toxins are the kalicludines from Anemonia sulcata, which selectively block Kv1.2 channels, [5 ] and SHTX II from…
23. 3. 2023Thank you, Cloé Dauplais ! We meant every word. We're fortunate to have you in our ranks, and we're thrilled to be one of your top clients. We'll keep rising up to the standard