Interleukin 15 (IL-15) byl v roce 1994 objeven a charakterizován jako růstový faktor buněk. IL-15 je 14 - 15 kDa velký glykoprotein, který svoji terciární strukturou patří do rodiny cytokinů obsahujících čtyři alfa-helixové domény. Kromě IL-15 se do této rodiny cytokinů řadí také interleukin-2 (IL-2),…

Interleukin 15 - Wikipedia

RLI-15 demonstrated a strong anti-tumor effect in two different tumor models. [51 ] RLI-15 is being produced and tested by Cytune Pharma affiliated company of Sotio which renamed it to SO-C101, later to SOT101. [52 ] Phase 1 trial was…

Interleukin-15 receptor - Wikipedia

The IL-15 receptor is composed of the IL-2Rβ and γc subunits, along with a unique ligand-specific subunit, IL-15Rα, which bears homology to IL-2Rα.

Interleukin 15-like - Wikipedia

Interleukin 15-like (IL-15L) is an interleukin, a type of cytokine signaling in the immune system. It is a secreted protein of approximately 120 amino acids [1 ] and related to IL-2 and IL-15.

Expression of interleukin-15 in human skeletal muscle – effect…

The cytokine interleukin-15 (IL-15) has been demonstrated to have anabolic effects in cell culture systems. We tested the hypothesis that IL-15 is predominantly expressed by type 2 skeletal muscle fibres, and that resistance exercise…

Interleukin-15 Treatment Induces Weight Loss Independent of…

Obesity is a chronic inflammatory condition characterized by activation and infiltration of proinflammatory immune cells and a dysregulated production of proinflammatory cytokines.

Interleukin-15, IL-15 Receptor-Alpha, and Obesity: Concordance…

Interleukin-15 (IL-15) is a cytokine which inhibits lipid deposition in cultured adipocytes and decreases adipose tissue deposition in laboratory rodents. In human subjects, negative correlations between circulating IL-15 levels and both…

Role of the marek’s disease virus (MDV) interleukin-8 (vIL-8…

Kniha Role of the marek’s disease virus (MDV) interleukin-8 (vIL-8) in lymphoma formation and recruitment of target cells z druhé ruky. Na Knihobotu seženete bestsellery, klasiku i raritky, které jinde nenajdete.
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interleukin 15 | Velký lékařský slovník On-Line

Interleukin 15 IL-15 – interleukin funkcí podobný IL-2 se stimulačními efekty na imunitní odpověď, lymfocyty, NK buňky. Produkován různými buňkami, např. endoteliálními, mononukleárními, endotelem

Medvik: Interleukin 15 a jeho analogy v protinádorové…

Medvik: Interleukin 15 a jeho analogy v protinádorové imunoterapii
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