Joel Fletcher | Cited by 28,344 | of Mayo Foundation for Medical Education and Research, Rochester (MMS) | Read 542 publications | Contact Joel Fletcher
The MRE11A-RAD50-Nibrin (MRN) complex plays several critical roles related to repair of DNA double-strand breaks. Inherited mutations in the three components predispose to genetic instability disorders and the MRN genes have been implicated…
It has a structural analog, deoxyribose, which is a similarly essential component of DNA. l-ribose is an unnatural sugar that was first prepared by Emil Fischer and Oscar Piloty in 1891. [4 ] It was not until 1909 that Phoebus Levene and…
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